What is intrauterine insemination (IUI)?
Artificial insemination or intrauterine insemination (IUI) involves inserting the male partner’s (or donor’s) concentrated sperm sample through cervix and into the cavity of the uterus, just at the perfect time before ovulation.
Who is IUI suitable for?
IUI is often recommended when using donor sperm, in the setting of sexual difficulties, or for unexplained infertility as a less effective but also less invasive intervention.
Artificial insemination using a sperm donor is an option for single women or same sex and gender diverse couples.
In some situations when sperm was frozen, for example, prior to a male partner’s chemotherapy treatment or long-term travel, IUIs can be used for the purpose of conception.

IUI step by step process
There are several methods to carry out this treatment.
- During a natural cycle, which is performed in sync with the woman’s regular menstrual cycle and involves no medication.
- Using hormonal stimulation (ovulation induction). This method stimulates the ovaries using oral medications (Such as Letrozole) or injections (such as follicle-stimulating hormones) in order to initiate or control ovulation.
If appropriate, we'll discuss the best approach in your circumstances.
- The woman’s cycle is monitored to determine the day of ovulation – this is often referred to as ‘cycle tracking’. Once the follicle is mature, ovulation is triggered by an injection of synthetic human chorionic gonadotropin (HCG).
- The sperm sample is analysed and washed to concentrate the number of mobile sperm. This prepared sperm is then inserted directly into the uterine cavity using a very thin catheter.
There is no need to miss time from work after the procedure, and the discomfort level is comparable to that of a pap smear.